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Article

Natural killer-cell deficiency alters placental development in rats†

23 Dec 2016

Abstract excerpt

Natural killer (NK) cells are the most prevalent leukocyte population in the uterus during early pregnancy. Natural killer cells contribute to uterine vascular (spiral artery) remodeling in preparation for the increased demand on these vessels later in pregnancy. A second wave of spiral artery modification is directed by invasive trophoblast cells. The significance of the initial wave of NK-cell-mediated vascular...

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PMID: 28395334
DOI: 10.1095/biolreprod.116.142752

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