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SCG5 and MITF may be novel markers of copper metabolism immunorelevance in Alzheimer’s disease

13 Jun 2024

Abstract excerpt

The slow-developing neurological disorder Alzheimer's disease (AD) has no recognized etiology. A bioinformatics investigation verified copper metabolism indicators for AD development. GEO contributed AD-related datasets GSE1297 and GSE5281. Differential expression analysis and WGCNA confirmed biomarker candidate genes. Each immune cell type in AD and control samples was scored using single sample gene set...

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PMID: 38871989
DOI: 10.1038/s41598-024-64599-z

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