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Article

Temporal and spatial dynamics of Plasmodium falciparum clonal lineages in Guyana.

PLoS pathogens - 1 Jun 2024

Vanhove Mathieu, Schwabl Philipp, Clementson Collette, Early Angela M, Laws Margaret, Anthony Frank, Florimond Célia, Mathieu Luana, James Kashana, Knox Cheyenne, Singh Narine, Buckee Caroline O, Musset Lise, Cox Horace, Niles-Robin Reza, Neafsey Daniel E

Abstract excerpt

Plasmodium parasites, the causal agents of malaria, are eukaryotic organisms that obligately undergo sexual recombination within mosquitoes. In low transmission settings, parasites recombine with themselves, and the clonal lineage is propagated rather than broken up by outcrossing. We investigated whether stochastic/neutral factors drive the persistence and abundance of Plasmodium falciparum clonal lineages in...

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PMID: 38870266
DOI: 10.1371/journal.ppat.1012013
PMCID: PMC11206942

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Source receipt: pubmed, retrieved 7 Sept 2026.

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