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Article

Parasite population dynamics shaped P. falciparum pfhrp2 and pfhrp3 deletion expansion in the Peruvian Amazon.

Scientific reports - 24 Apr 2026

Figueroa-Ildefonso Erick, Cabrera-Sosa Luis, Kattenberg Johanna H, Valdivia Hugo O, Delgado-Ratto Christopher, Rosanas-Urgell Anna, Gamboa Dionicia

Abstract excerpt

Plasmodium falciparum populations in the Peruvian Amazon have undergone changes in the last 20 years, coinciding with the implementation of the PAMAFRO malaria control program (2005-2011). In this context, parasites with deletions of the pfhrp2 and pfhrp3 (pfhrp2/3) genes, involved in rapid diagnostic test (RDT) failure, have been increasingly predominant in Peru since 2012. Here, we investigated population...

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Identifiers

PMID: 42031913
DOI: 10.1038/s41598-026-48246-3
PMCID: PMC13392378

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