Resolving drug selection and migration in an inbred South American Plasmodium falciparum population with identity-by-descent analysis

Abstract excerpt

The human malaria parasite Plasmodium falciparum is globally widespread, but its prevalence varies significantly between and even within countries. Most population genetic studies in P. falciparum focus on regions of high transmission where parasite populations are large and genetically diverse, such as sub-Saharan Africa. Understanding population dynamics in low transmission settings, however, is of particular...

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