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Association of ACE2 and TMPRSS2 genes variants with disease severity and most important biomarkers in COVID-19 patients in Bosnia and Herzegovina.

Croatian medical journal - 13 Jun 2024

Meseldžić Neven, Prnjavorac Besim, Dujić Tanja, Malenica Maja, Glamočlija Una, Prnjavorac Lejla, Bedak Omer, Imamović Kadrić Selma, Marjanović Damir, Bego Tamer

Abstract excerpt

AIM: To assess the association of single nucleotide polymorphisms (SNPs) in the ACE2 and TMPRSS2 genes with COVID-19 severity and key biomarkers. METHODS: The study involved 750 COVID-19 patients from Bosnia and Herzegovina, divided into three groups: mild, moderate, and severe cases. Genetic variations within the ACE2 (rs2285666) and TMPRSS2 (rs2070788) genes were examined with real-time polymerase chain...

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PMID: 38868968
PMCID: PMC11157263

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