The emerging challenge of FLiRT variants: KP.1.1 and KP.2 in the global pandemic landscape.

doi:10.1093/qjmed/hcae102

Article

The emerging challenge of FLiRT variants: KP.1.1 and KP.2 in the global pandemic landscape.

QJM : monthly journal of the Association of Physicians - 1 Jul 2024

Kumar P, Jayan J, Sharma R K, Gaidhane A M, Zahiruddin Q S, Rustagi S, Satapathy P

Abstract excerpt

The SARS-CoV-2 virus has undergone substantial evolution, leading to emergence of new FLiRT variants characterized by specific spike mutations-F to L at position 456 and R to T at position 346-enhancing their transmissibility and immune evasion capabilities. Particularly, KP.2 shows a significant increase in cases in the USA, indicating a potential shift in the pandemic landscape due to its greater ability to...

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The emerging challenge of FLiRT variants: KP.1.1 and KP.2 in the global pandemic landscape.

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