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Article

The biological and clinical significance of emerging SARS-CoV-2 variants.

Nature reviews. Genetics - 1 Dec 2021

Tao Kaiming, Tzou Philip L, Nouhin Janin, Gupta Ravindra K, de Oliveira Tulio, Kosakovsky Pond Sergei L, Fera Daniela, Shafer Robert W

Abstract excerpt

The past several months have witnessed the emergence of SARS-CoV-2 variants with novel spike protein mutations that are influencing the epidemiological and clinical aspects of the COVID-19 pandemic. These variants can increase rates of virus transmission and/or increase the risk of reinfection and reduce the protection afforded by neutralizing monoclonal antibodies and vaccination. These variants can therefore...

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Biological Evolution
COVID-19
COVID-19 Clinical Research Studies
Epitopes
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

SARS-CoV-2 and COVID-19 Research

Spike Glycoprotein, Coronavirus

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Identifiers

PMID: 34535792
DOI: 10.1038/s41576-021-00408-x
PMCID: PMC8447121

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