Cost-Effectiveness of Unselected Multigene Germline and Somatic Genetic Testing for Epithelial Ovarian Cancer.

doi:10.6004/jnccn.2023.7331

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Article

Cost-Effectiveness of Unselected Multigene Germline and Somatic Genetic Testing for Epithelial Ovarian Cancer.

Journal of the National Comprehensive Cancer Network : JNCCN - 18 Apr 2024

Manchanda Ranjit, Sun Li, Sobocan Monika, Rodriguez Isabel V, Wei Xia, Kalra Ashwin, Oxley Samuel, Sideris Michail, Fierheller Caitlin T, Morgan Robert D, Chandrasekaran Dhivya, Rust Kelly, Spiliopoulou Pavlina, Miller Rowan E, Crusz Shanthini M, Lockley Michelle, Singh Naveena, Faruqi Asma, Casey Laura, Brockbank Elly, Phadnis Saurabh, Mills-Baldock Tina, El-Khouly Fatima, Jenkins Lucy A, Wallace Andrew, Ahmed Munaza, Kumar Ajith, Swisher Elizabeth M, Gourley Charlie, Norquist Barbara M, Evans D Gareth, Legood Rosa

Abstract excerpt

BACKGROUND: Parallel panel germline and somatic genetic testing of all patients with ovarian cancer (OC) can identify more pathogenic variants (PVs) that would benefit from PARP inhibitor (PARPi) therapy, and allow for precision prevention in unaffected relatives with PVs. In this study, we estimate the cost-effectiveness and population impact of parallel panel germline and somatic BRCA testing of all patients...

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PMID: 38866043
DOI: 10.6004/jnccn.2023.7331

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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