Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Implementation of Multigene Germline and Parallel Somatic Genetic Testing in Epithelial Ovarian Cancer: SIGNPOST Study

27 Aug 2021

Abstract excerpt

We present findings of a cancer multidisciplinary-team (MDT) coordinated mainstreaming pathway of unselected 5-panel germline BRCA1/BRCA2/RAD51C/RAD51D/BRIP1 and parallel somatic BRCA1/BRCA2 testing in all women with epithelial-OC and highlight the discordance between germline and somatic testing strategies across two cancer centres. Patients were counselled and consented by a cancer MDT member. The uptake of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to BRCA gene mutations in cancer
Share to Cancer Genomics and Diagnostics
Share to Ovarian cancer diagnosis and treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34503154
DOI: 10.3390/cancers13174344

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Implementation of Multigene Germline and Parallel Somatic Genetic Testing in Epithelial Ovarian Cancer: SIGNPOST StudyPMID 34503154Read ↗

Multigene Panel Germline Testing of 1333 Czech Patients with Ovarian CancerSemantic proximity Read ↗

British Gynaecological Cancer Society/British Association of Gynaecological Pathology consensus for germline and tumor testing for BRCA1/2 variants in ovarian cancer in the United Kingdom.Semantic proximity Read ↗

Optimizing the detection of hereditary predisposition in women with epithelial ovarian cancer: nationwide implementation of the Tumor-First workflow.Semantic proximity Read ↗

Update: variable implementation of the 2018 UKCGG/UKGTN guidelines for breast cancer gene panel tests offered by UK genetics services.Semantic proximity Read ↗

Exploring the somatic mutational landscape of ovarian cancer in Estonia.Semantic proximity Read ↗

Mainstreaming germline BRCA1/2 testing in non-mucinous epithelial ovarian cancer in the North West of EnglandSemantic proximity Read ↗

Genetic testing for epithelial ovarian cancer.Semantic proximity Read ↗

Nationwide implementation and evaluation of the Tumor-First workflow for genetic testing in ovarian carcinoma.Semantic proximity Read ↗

Germline and somatic testing for ovarian Cancer: An SGO clinical practice statementSemantic proximity Read ↗

Detection of Germline Mutations in Patients with Epithelial Ovarian Cancer Using Multi-gene Panels: Beyond BRCA1/2Semantic proximity Read ↗

Unrecognised actionability for breast cancer risk variants identified in a national-level review of Australian familial cancer centresSemantic proximity Read ↗

Frequency of mutations in a large series of clinically ascertained ovarian cancer cases tested on multi-gene panels compared to reference controls.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.