Article
Changes to social feeding behaviors are not sufficient for fitness gains of the Caenorhabditis elegans N2 reference strain.
eLife - 17 Oct 2018
Zhao Yuehui, Long Lijiang, Xu Wen, Campbell Richard F, Large Edward E, Greene Joshua S, McGrath Patrick T
Abstract excerpt
The standard reference Caenorhabditis elegans strain, N2, has evolved marked behavioral changes in social feeding behavior since its isolation from the wild. We show that the causal, laboratory-derived mutations in two genes, npr-1 and glb-5, confer large fitness advantages in standard laboratory conditions. Using environmental manipulations that suppress social/solitary behavior differences, we show the fitness...
Topics
- Alleles
- Animals
- Behavior, Animal
- Caenorhabditis elegans
- Feeding Behavior
- Gene Expression Regulation
- Genes, Helminth
- Genetic Fitness
- Neurons
- Organ Size
- Oxygen