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Multi-omics analysis uncovered systemic lupus erythematosus and COVID-19 crosstalk

11 Jun 2024

Abstract excerpt

BACKGROUND: Studies have highlighted a possible crosstalk between the pathogeneses of COVID-19 and systemic lupus erythematosus (SLE); however, the interactive mechanisms remain unclear. We aimed to elucidate the impact of COVID-19 on SLE using clinical information and the underlying mechanisms of both diseases. METHODS: RNA-seq datasets were used to identify shared hub gene signatures between COVID-19 and SLE,...

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PMID: 38862942
DOI: 10.1186/s10020-024-00851-6

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