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Identification of differentially expressed immune-related genes in patients with systemic lupus erythematosus and the development of a hub gene-based diagnostic model

30 Jul 2025

Abstract excerpt

BACKGROUND: Systemic lupus erythematosus (SLE) is an incurable autoimmune disease that affects body tissues, but it can be managed with medication. Although therapeutic strategies for SLE have advanced, the underlying molecular mechanisms driving disease pathogenesis remain incompletely understood. METHODS: This study analyzed gene expression data from three GEO microarray datasets to explore immunity-related...

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interferon and immune responses
Spondyloarthritis Studies and Treatments
Systemic Lupus Erythematosus Research

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40739239
DOI: 10.1186/s40001-025-02953-1

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