Article
Association between gut microbiota and CpG island methylator phenotype in colorectal cancer.
Gut microbes - 1 Jan 2000
Park Pyoung Hwa, Keith Kelsey, Calendo Gennaro, Jelinek Jaroslav, Madzo Jozef, Gharaibeh Raad Z, Ghosh Jayashri, Sapienza Carmen, Jobin Christian, Issa Jean-Pierre J
Abstract excerpt
The intestinal microbiota is an important environmental factor implicated in CRC development. Intriguingly, modulation of DNA methylation by gut microbiota has been reported in preclinical models, although the relationship between tumor-infiltrating bacteria and CIMP status is currently unexplored. In this study, we investigated tumor-associated bacteria in 203 CRC tumor cases and validated the findings using The...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
