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Quantifying variation across 16S rRNA gene sequencing runs in human microbiome studies

8 Jun 2024

Abstract excerpt

Recent microbiome research has incorporated a higher number of samples through more participants in a study, longitudinal studies, and metanalysis between studies. Physical limitations in a sequencing machine can result in samples spread across sequencing runs. Here we present the results of sequencing nearly 1000 16S rRNA gene sequences in fecal (stabilized and swab) and oral (swab) samples from multiple human...

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PMID: 38850297
DOI: 10.1007/s00253-024-13198-z

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