Article
Genetic Analysis of the X Chromosome Associates Loci with Progression of Parkinson's Disease.
Movement disorders : official journal of the Movement Disorder Society - 1 Sept 2025
Liao Yu, Wu Hao, Wang Junhao, Corvol Jean-Christophe, Maple-Grødem Jodi, Campbell Meghan C, Elbaz Alexis, Brice Alexis, Schwarzschild Michael A, Taba Pille, Kõks Sulev, Beach Thomas G, Alves Guido, Tysnes Ole-Bjørn, Perlmutter Joel S, Maiti Baijayanta, van Hilten Jacobus J, Barker Roger A, Williams-Gray Caroline H, Scherzer Clemens R, Liu Ganqiang
Abstract excerpt
BACKGROUND: Genetic variants on the X chromosome have been linked to susceptibility for Parkinson's disease (PD), but their roles in disease progression remain unclear. OBJECTIVES: This study investigated associations between X chromosome variants and longitudinal cognitive decline or motor impairment in patients with PD. METHODS: We conducted combined (male + female) and stratified X-chromosome-wide survival...
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