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Implementation of Universal Pan-Cancer Germline Genetic Testing in an Arab Population: The Jordanian Exploratory Cancer Genetics Study.

JCO global oncology - 1 Jun 2024

Abdel-Razeq Hikmat, Sharaf Baha', Bani Hani Hira, Abu Hijlih Ramiz, Alkyam Mais, Al-Azzam Khansa, Elemian Shatha, Tbakhi Abdelghani, Al-Atary Areej, Ellsworth Rachel E, Russell Emily M, Esplin Edward D, Horani Malek, Zeidan Zeidan, Alzibdeh Abdulla, Heald Brandie, Nielsen Sarah M, Nussbaum Robert L

Abstract excerpt

PURPOSE: Germline genetic testing (GGT) significantly affects cancer care. While universal testing has been studied in Western societies, less is known about adoption elsewhere. MATERIALS AND METHODS: In this study, 3,319 unselected, pan-cancer Jordanian patients diagnosed between April 2021 and September 2022 received GGT. Pathogenic germline variant (PGV) frequency among patients who were in-criteria (IC) or...

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PMID: 38843472
DOI: 10.1200/GO.24.00068

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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