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Article

Causal associations between platelet count, alcohol consumption, and the risk of liver hepatocellular carcinoma based on a Mendelian randomization study.

Frontiers in endocrinology - 1 Jan 2024

Yu Lihua, Wang Leisheng, Xue Yuzheng, Ren Yilin, Liu Tianhao, Hu Hao

Abstract excerpt

Background and aims: Liver hepatocellular carcinoma (LIHC) exhibits a multifactorial etiology, insidious onset, and a significantly low 5-year survival rate. We aimed to evaluate the causal impact of exposure factors (Alzheimer's disease, platelet count, ambidextrousness, cigarettes smoked per day, alcohol consumption, and endocarditis) on the risk of LIHC using a two-sample Mendelian randomization (MR) study....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38841303
DOI: 10.3389/fendo.2024.1400573
PMCID: PMC11151168

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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