Article
Case-Case Genome-Wide Analyses Identify Subtype-Informative Variants That Confer Risk for Breast Cancer.
Cancer research - 1 Aug 2024
Sun Xiaohui, Verma Shiv P, Jia Guochong, Wang Xinjun, Ping Jie, Guo Xingyi, Shu Xiao-Ou, Chen Jianhong, Derkach Andriy, Cai Qiuyin, Liang Xiaolin, Long Jirong, Offit Kenneth, Oh Jung H, Reiner Anne S, Watt Gordon P, Woods Meghan, Yang Yaohua, Ambrosone Christine B, Ambs Stefan, Chen Yu, Concannon Patrick, Garcia-Closas Montserrat, Gu Jian, Haiman Christopher A, Hu Jennifer J, Huo Dezheng, John Esther M, Knight Julia A, Li Christopher I, Lynch Charles F, Mellemkjær Lene, Nathanson Katherine L, Nemesure Barbara, Olopade Olufunmilayo I, Olshan Andrew F, Pal Tuya, Palmer Julie R, Press Michael F, Sanderson Maureen, Sandler Dale P, Troester Melissa A, Zheng Wei, Bernstein Jonine L, Buas Matthew F, Shu Xiang
Abstract excerpt
Breast cancer includes several subtypes with distinct characteristic biological, pathologic, and clinical features. Elucidating subtype-specific genetic etiology could provide insights into the heterogeneity of breast cancer to facilitate the development of improved prevention and treatment approaches. In this study, we conducted pairwise case-case comparisons among five breast cancer subtypes by applying a...
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