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Article

Involvement of RAGE in radiation-induced acquisition of malignant phenotypes in human glioblastoma cells.

Biochimica et biophysica acta. General subjects - 1 Sept 2024

Seki Hiromu, Kitabatake Kazuki, Tanuma Sei-Ichi, Tsukimoto Mitsutoshi

Abstract excerpt

Glioblastoma (GBM), a highly aggressive malignant tumor of the central nervous system, is mainly treated with radiotherapy. However, since irradiation may lead to the acquisition of migration ability by cancer cells, thereby promoting tumor metastasis and invasion, it is important to understand the mechanism of cell migration enhancement in order to prevent recurrence of GBM. The receptor for advanced glycation...

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PMID: 38830560
DOI: 10.1016/j.bbagen.2024.130650

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