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Article

MMP14 Contributes to HDAC Inhibition-Induced Radiosensitization of Glioblastoma

27 Sept 2021

Abstract excerpt

Glioblastoma (GBM) is the most common and malignant primary brain tumor in adults. Radiotherapy has long been an important treatment method of GBM. However, the intrinsic radioresistance of GBM cells is a key reason of poor therapeutic efficiency. Recently, many studies have shown that using the histone deacetylase (HDAC) inhibitor suberoylanilide hydroxamic acid (SAHA) in radiotherapy may improve the prognosis...

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Share to Epigenetics and DNA Methylation
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PMID: 34638754
DOI: 10.3390/ijms221910403

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