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Article

β-Sitosterol alleviates the malignant phenotype of hepatocellular carcinoma cells via inhibiting GSK3B expression.

Human cell - 1 Jul 2024

Wang Ruoyu, Tang Dan, Ou Longyun, Jiang Jiacheng, Wu Yu-Nan, Tian Xuefei

Abstract excerpt

To explore the effects of β-Sitosterol upon hepatocellular carcinoma cell proliferation, apoptosis, migration, invasion, and epithelial-mesenchymal transition (EMT), and to investigate the underlying mechanism using network pharmacology. Human hepatocellular carcinoma cell lines (Huh-7 and HCCLM3) were expose to gradient concentrations of β-Sitosterol (5 μg/mL, 10 μg/mL, and 20 μg/mL). Cell viability and...

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Share to Apoptosis
Share to Carcinoma, Hepatocellular
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38814517
DOI: 10.1007/s13577-024-01081-y
PMCID: PMC11194219

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