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Article

Potentially functional genetic variants in interferon regulatory factor family genes are associated with colorectal cancer survival.

Molecular carcinogenesis - 1 Sept 2024

Tong Xiaoxia, Li Chenghui, Ma Li, Wu Di, Liu Yonglei, Zhao Liqin, Wang Mengyun

Abstract excerpt

Interferon regulatory factor (IRF) family genes play a critical role in colorectal cancer (CRC) development and impact patient survival. This study evaluated the influence of functional single nucleotide polymorphisms (SNPs) in IRF genes on CRC survival, including functional predictions and experimental validations. Multivariate Cox regression analysis identified three linked SNPs as significant survival...

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Identifiers

PMID: 38812445
DOI: 10.1002/mc.23752

Genes

MIF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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