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Interferon regulatory factor family influences tumor immunity and prognosis of patients with colorectal cancer

6 Sept 2021

Abstract excerpt

Abstract Background Since interferon regulatory factor (IRF) family functions in immune response to viral infection, its role in colorectal cancer (CRC) has not been inspected before. This study tries to investigate members of IRF family using bioinformatics approaches in aspect of differential expressions, biological function, tumor immune infiltration and clinical prognostic value for patients with CRC. Methods...

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PMID: 34488791
DOI: 10.1186/s12967-021-03054-3

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