Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Zika Virus NS5 Forms Supramolecular Nuclear Bodies That Sequester Importin-α and Modulate the Host Immune and Pro-Inflammatory Response in Neuronal Cells

8 Mar 2019

Abstract excerpt

The Zika virus (ZIKV) epidemic in the Americas was alarming because of its link with microcephaly in neonates and Guillain-Barré syndrome in adults. The unusual pathologies induced by ZIKV infection and the knowledge that the flaviviral nonstructural protein 5 (NS5), the most conserved protein in the flavivirus proteome, can modulate the host immune response during ZIKV infection prompted us to investigate the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to HIV Research and Treatment
Share to Mosquito-borne diseases and control
Share to Viral Infections and Vectors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30848123
DOI: 10.1021/acsinfecdis.8b00373

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Zika Virus NS5 Forms Supramolecular Nuclear Bodies That Sequester Importin-α and Modulate the Host Immune and Pro-Inflammatory Response in Neuronal CellsPMID 30848123Read ↗

The Potential Role of the ZIKV NS5 Nuclear Spherical-Shell Structures in Cell Type-Specific Host Immune Modulation during ZIKV InfectionSemantic proximity Read ↗

Zika virus NS5 nuclear accumulation is protective of protein degradation and is required for viral RNA replicationSemantic proximity Read ↗

Host cytoskeletal vimentin serves as a structural organizer and an RNA-binding protein regulator to facilitate Zika viral replicationSemantic proximity Read ↗

Zika virus NS3 drives the assembly of a viroplasm-like structureSemantic proximity Read ↗

Flavivirus Capsid Proteins Inhibit the Interferon ResponseSemantic proximity Read ↗

Network of Interactions between ZIKA Virus Non-Structural Proteins and Human Host ProteinsSemantic proximity Read ↗

Host cytoskeletal vimentin serves as a structural organizer and an RNA-binding protein regulator to facilitate Zika viral replicationSemantic proximity Read ↗

Atlastin Endoplasmic Reticulum-Shaping Proteins Facilitate Zika Virus ReplicationSemantic proximity Read ↗

Zika virus proteins at an atomic scale: how does structural biology help us to understand and develop vaccines and drugs against Zika virus infection?Semantic proximity Read ↗

Serotype-Specific Regulation of Dengue Virus NS5 Protein Subcellular LocalizationSemantic proximity Read ↗

Structure and function of the Zika virus full-length NS5 proteinSemantic proximity Read ↗

NS5 Sumoylation Directs Nuclear Responses That Permit Zika Virus To Persistently Infect Human Brain Microvascular Endothelial Cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.