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Epstein-Barr Virus Sequence Variations Among the Understudied Nasopharyngeal Carcinoma Patients of Diverse Ancestries in Southeast Asia.

Journal of medical virology - 1 Mar 2025

Tee Hwee Sze, Liang Jingtong, Aziz Norazlin Abdul, Zhou Xiang, Hisham Hamidah Akmal, Tan Ke-En, Chen Yanhong, Burhanuddin Zuriani, Kwan Johnny S H, Lo Kwok-Wai, Hassan Faridah, Bt Mohd Mokhtar Sha'ariyah, Khoo Alan Soo Beng, Xu Miao, Lim Yat-Yuen, Tan Lu Ping

Abstract excerpt

Epstein-Barr virus (EBV) is associated with cancers, including lymphomas and nasopharyngeal carcinoma (NPC). To date, risk variants for NPC were mainly identified from Chinese populations, which dominated the world's total number of cases. Although Southeast Asia (SEA) countries have among the world's top yet intriguingly diverse NPC age-standardized incidence rates across subpopulations, data on EBV from SEA...

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PMID: 40042148
DOI: 10.1002/jmv.70269
PMCID: PMC11881214

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