Article
Mendelian randomization analyses reveal no genetic causal effects of major adipokines on systemic lupus erythematosus.
PloS one - 1 Jan 2024
Duan Peng, Tian Suyan
Abstract excerpt
Epidemiological studies have shown that the levels of serum adipokine such as leptin and resistin are associated with the risk of developing systemic lupus erythematosus (SLE). Nevertheless, whether either leptin or resistin has causal impacts on the risk of SLE is still unknown. In this study, two-sample univariable MR analyses and multivariable MR analysis were performed to explore the causal relationships...
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