Article
Trans-ethnic Mendelian randomization study of systemic lupus erythematosus and common female hormone-dependent malignancies.
Chinese medical journal - 5 Nov 2023
Zhu Tingting, Ding Yantao, Xu Xiaoli, Zhang Liyin, Zhang Xuejun, Cui Yong, Liu Lu
Abstract excerpt
BACKGROUND: Observational research has reported that systemic lupus erythematosus (SLE) is related to common female hormone-dependent cancers, but the underlying causal effect remains undefined. This study aimed to explore the causal association of these conditions by Mendelian randomization (MR) analysis. METHODS: We selected instrumental variables for SLE from genome-wide association studies (GWASs) conducted...
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