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The intricate interplay between cancer stem cells and cell-of-origin of cancer: implications for therapeutic strategies

10 May 2024

Abstract excerpt

Background: Cancer stem cells (CSCs) have emerged as pivotal players in tumorigenesis, disease progression, and resistance to therapies. Objective: This comprehensive review delves into the intricate relationship between CSCs and the cell-of-origin in diverse cancer types. Design: Comprehensive review of thematically-relevant literature. Methods: We explore the underlying molecular mechanisms that drive the...

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Identifiers

PMID: 38800385
DOI: 10.3389/fonc.2024.1404628

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