Article
Gain-Type Aneuploidies Influence the Burden of Selective Long Non-Coding Transcripts in Colorectal Cancer.
International journal of molecular sciences - 19 May 2024
Scuderi Chiara, Di Bella Virginia, Privitera Anna Provvidenza, Giustolisi Francesca Maria, Barresi Vincenza, Condorelli Daniele Filippo
Abstract excerpt
Chromosomal instability is a hallmark of colorectal carcinogenesis and produces an accumulation of different forms of aneuploidies or broad copy number aberrations. Colorectal cancer is characterized by gain-type broad copy number aberrations, specifically in Chr20, Chr8q, Chr13 and Chr7, but their roles and mechanisms in cancer progression are not fully understood. It has been suggested that broad copy number...
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