Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interleukin-1β Polymorphisms Are Genetic Markers of Susceptibility to Periprosthetic Joint Infection in Total Hip and Knee Arthroplasty.

Genes - 8 May 2024

Granata Valentina, Strina Dario, Possetti Valentina, Leone Roberto, Valentino Sonia, Chiappetta Katia, Loppini Mattia, Mantovani Alberto, Bottazzi Barbara, Asselta Rosanna, Sobacchi Cristina, Inforzato Antonio

Abstract excerpt

Periprosthetic joint infections (PJIs) are serious complications of prosthetic surgery. The criteria for the diagnosis of PJI integrate clinical and laboratory findings in a complex and sometimes inconclusive workflow. Host immune factors hold potential as diagnostic biomarkers in bone and joint infections. We reported that the humoral pattern-recognition molecule long pentraxin 3 (PTX3) predicts PJI in total hip...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arthroplasty, Replacement, Hip
Share to Arthroplasty, Replacement, Knee

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to C-Reactive Protein

Share to Case-Control Studies

Share to Genetic Markers

Share to Interleukin-1beta

Share to Prosthesis-Related Infections

Share to Serum Amyloid P-Component

Source

Open in PubMed Open full text

Identifiers

PMID: 38790226
DOI: 10.3390/genes15050596
PMCID: PMC11120921

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interleukin-1β Polymorphisms Are Genetic Markers of Susceptibility to Periprosthetic Joint Infection in Total Hip and Knee Arthroplasty.PMID 38790226Read ↗

IL-1 β gene (+3954 C/T, exon 5, rs1143634) and NOS2 (exon 22) polymorphisms associate with early aseptic loosening of arthroplasties.Semantic proximity Read ↗

Genetic variation in key molecules of the Th-17 immune response is not associated with risk for prosthetic joint infection in a Czech population.Semantic proximity Read ↗

Single nucleotide polymorphisms in the development of osteomyelitis and prosthetic joint infection: a narrative review.Semantic proximity Read ↗

Variation in the IL1B, TNF and IL6 genes and individual susceptibility to prosthetic joint infection.Semantic proximity Read ↗

Assessment of IL-10, IL-1ß and TNF-α gene polymorphisms in patients with peri-implantitis and healthy controls.Semantic proximity Read ↗

Integrating Genome-Wide Polygenic Risk Scores With Nongenetic Models to Predict Surgical Site Infection After Total Knee Arthroplasty Using United Kingdom Biobank Data.Semantic proximity Read ↗

Aseptic Loosening in Total Hip Arthroplasty: Pathophysiology, Biomarkers, and Preventive Treatment StrategiesSemantic proximity Read ↗

Association of IL-10 and TNF-α Polymorphisms with Dental Peri-Implant Disease Risk: A Meta-Analysis, Meta-Regression, and Trial Sequential Analysis.Semantic proximity Read ↗

Diagnostic Value of Next-Generation Sequencing to Detect Periprosthetic Joint InfectionSemantic proximity Read ↗

Synovial fluid S100A8, S100A9, and HNP 1-3 in the diagnosis of periprosthetic joint infection: a prospective, double-blind trialSemantic proximity Read ↗

Genetic susceptibility to prosthetic joint infection following total joint arthroplasty: A systematic review.Semantic proximity Read ↗

Human prosthetic joint infections are associated with myeloid‐derived suppressor cells (MDSCs): Implications for infection persistenceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.