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Article

Proteome-wide Mendelian randomization identifies potential therapeutic targets for nonalcoholic fatty liver diseases.

Scientific reports - 23 May 2024

Li Junhang, Ma Xiang, Yin Cuihua

Abstract excerpt

Nonalcoholic fatty liver disease (NAFLD) is the predominant cause of liver pathology. Current evidence highlights plasma proteins as potential therapeutic targets. However, their mechanistic roles in NAFLD remain unclear. This study investigated the involvement of specific plasma proteins and intermediate risk factors in NAFLD progression. Two-sample Mendelian randomization (MR) analysis was conducted to examine...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38782984
DOI: 10.1038/s41598-024-62742-4
PMCID: PMC11116402

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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