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Article

Exploring the interconnected between type 2 diabetes mellitus and nonalcoholic fatty liver disease: Genetic correlation and Mendelian randomization analysis.

Medicine - 10 May 2024

Ni Wenjuan, Lu Yao, Wang Wei

Abstract excerpt

Epidemiological and clinical studies have indicated a higher risk of nonalcoholic fatty liver disease (NAFLD) and type 2 diabetes mellitus (T2DM), implying a potentially shared genetic etiology, which is still less explored. Genetic links between T2DM and NAFLD were assessed using linkage disequilibrium score regression and pleiotropic analysis under composite null hypothesis. European GWAS data have identified...

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Share to Diabetes Mellitus, Type 2
Share to Genetic Pleiotropy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Linkage Disequilibrium

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Share to Non-alcoholic Fatty Liver Disease

Share to Polymorphism, Single Nucleotide

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Source

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Identifiers

PMID: 38728519
DOI: 10.1097/MD.0000000000038008
PMCID: PMC11081543

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