Article
The best linear unbiased prediction (BLUP) method as a tool to estimate the lifetime risk of pancreatic ductal adenocarcinoma in high-risk individuals with no known pathogenic germline variants.
Familial cancer - 1 Aug 2024
Cristina-Marianini-Rios, Sanchez María E Castillo, de Paredes Ana García García, Rodríguez Mercedes, Barreto Emma, López Jorge Villalón, Fuentes Raquel, Beltrán María Muñoz, Sanjuanbenito Alfonso, Lobo Eduardo, Caminoa Alejandra, Ruz-Caracuel Ignacio, Durán Sergio López, Olcina José Ramón Foruny, Blázquez Javier, Sequeros Enrique Vázquez, Carrato Alfredo, Ávila Jose Carlos Martínez, Earl Julie
Abstract excerpt
Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer-related death in the Western world. The number of diagnosed cases and the mortality rate are almost equal as the majority of patients present with advanced disease at diagnosis. Between 4 and 10% of pancreatic cancer cases have an apparent hereditary background, known as hereditary pancreatic cancer (HPC) and familial pancreatic cancer...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.