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Article

Correlation of genomic alterations between tumor tissue and circulating tumor DNA by next-generation sequencing.

Journal of cancer research and clinical oncology - 1 Nov 2018

Chang Ya-Sian, Fang Hsin-Yuan, Hung Yao-Ching, Ke Tao-Wei, Chang Chieh-Min, Liu Ting-Yuan, Chen Yu-Chia, Chao Dy-San, Huang Hsi-Yuan, Chang Jan-Gowth

Abstract excerpt

PURPOSE: Analysis of circulating tumor DNA (ctDNA) offers an unbiased and noninvasive way to assess the genetic profiles of tumors. This study aimed to analyze mutations in ctDNA and their correlation with tissue mutations in patients with a variety of cancers. METHODS: We included 21 cancer patients treated with surgical resection for whom we collected paired tissue and plasma samples. Next-generation sequencing...

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Aged
Biomarkers, Tumor
Circulating Tumor DNA
Genome, Human
High-Throughput Nucleotide Sequencing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 30203147
DOI: 10.1007/s00432-018-2747-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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