Article
Humanin P3S, haplogroup N1b and the risk of Alzheimer's disease.
Aging cell - 1 Jul 2024
Logan Ian Stewart
Abstract excerpt
A commentary of the paper 'Humanin variant P3S is associated with longevity in APOE4 carriers and resists APOE4-induced brain pathology' that appeared recently in Aging Cell. The possible association of a mitochondrial haplogroup with a disease is frequently discussed. The Humanin peptide encoded by the mtDNA has been shown to play an important regulatory role in cell metabolism. There are variants of Humanin...
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