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Article

The miR-641-STIM1 and SATB1 axes play important roles in the regulation of the Th17/Treg balance in ITP

16 May 2024

Abstract excerpt

Immune thrombocytopenia (ITP) is an autoimmune disease caused by T-cell dysfunction. Recently, several studies have shown that a disturbed Th17/Treg balance contributes to the development of ITP. MicroRNAs (miRNAs) are small noncoding RNA moleculesthat posttranscriptionally regulate gene expression. Emerging evidences have demonstrated that miRNAs play an important role in regulating the Th17/Treg balance. In the...

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PMID: 38755179
DOI: 10.1038/s41598-024-61660-9

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