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Decreased expression of interleukin‐27 in immune thrombocytopenia

8 Mar 2011

Abstract excerpt

Primary immune thrombocytopenia (ITP) is an immune-mediated disorder in which disturbed cytokine profiles have been found. Interleukin-27 (IL27) has been shown to bear both proinflammatory and anti-inflammtory effects. In the present study, plasma levels of IL27, interferon gamma (IFNG), IL4, and IL17A were determined by enzyme-linked immunosorbent assay in 23 active ITP patients, 20 patients in remission and 20...

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PMID: 21385171
DOI: 10.1111/j.1365-2141.2011.08614.x

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