Article
Optimal fusion of genotype and drug embeddings in predicting cancer drug response.
Briefings in bioinformatics - 27 Mar 2024
Nguyen Trang, Campbell Anthony, Kumar Ankit, Amponsah Edwin, Fiterau Madalina, Shahriyari Leili
Abstract excerpt
Predicting cancer drug response using both genomics and drug features has shown some success compared to using genomics features alone. However, there has been limited research done on how best to combine or fuse the two types of features. Using a visible neural network with two deep learning branches for genes and drug features as the base architecture, we experimented with different fusion functions and fusion...
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