Article
Relationships between genomic dissipation and de novo SNP evolution.
PloS one - 1 Jan 2024
Plyler Zackery E, McAtee Christopher W, Hill Aubrey E, Crowley Michael R, Tindall Janice M, Tindall Samuel R, Joshi Disha, Sorscher Eric J
Abstract excerpt
Patterns of single nucleotide polymorphisms (SNPs) in eukaryotic DNA are traditionally attributed to selective pressure, drift, identity descent, or related factors-without accounting for ways in which bias during de novo SNP formation, itself, might contribute. A functional and phenotypic analysis based on evolutionary resilience of DNA points to decreased numbers of non-synonymous SNPs in human and other...
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