Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Even small SNP clusters are non-randomly distributed: is this evidence of mutational non-independence?

Proceedings. Biological sciences - 7 May 2010

Amos William

Abstract excerpt

Single nucleotide polymorphisms (SNPs) are distributed highly non-randomly in the human genome through a variety of processes from ascertainment biases (i.e. the preferential development of SNPs around interesting genes) to the action of mutation hotspots and natural selection. However, with more...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Evolution and Genetic Dynamics
Share to Genetic factors in colorectal cancer
Share to Genome, Human

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genomics and Chromatin Dynamics

Share to Models, Genetic

Share to Mutation

Share to Polymorphism, Single Nucleotide

Share to Stochastic Processes

Source

Open in PubMed Open full text

Identifiers

PMID: 20071383
DOI: 10.1098/rspb.2009.1757
PMCID: PMC2871933

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20071383-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Even small SNP clusters are non-randomly distributed: is this evidence of mutational non-independence?PMID 20071383Read ↗

A model for the clustered distribution of SNPs in the human genome.Semantic proximity Read ↗

Human triallelic sites: evidence for a new mutational mechanism?Semantic proximity Read ↗

Relationships between genomic dissipation and de novo SNP evolution.Semantic proximity Read ↗

[Non-random randomness].Semantic proximity Read ↗

Distribution of human SNPs and its effect on high-throughput genotyping.Semantic proximity Read ↗

Some probabilistic results on the nonrandomness of simple sequence repeats in DNA sequences.Semantic proximity Read ↗

Local similarity in evolutionary rates extends over whole chromosomes in human-rodent and mouse-rat comparisons: implications for understanding the mechanistic basis of the male mutation bias.Semantic proximity Read ↗

Microsatellites, transposable elements and the X chromosome.Semantic proximity Read ↗

Clusters of identical new mutations can account for the "overdispersed" molecular clock.Semantic proximity Read ↗

Testing of chromosomal clumping of gene properties.Semantic proximity Read ↗

Longevity and plasticity of CFTR provide an argument for noncanonical SNP organization in hominid DNA.Semantic proximity Read ↗

A test of allelic independence based on distributions of allele size differences at microsatellite loci.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.