Article
Functional characterization of variants in human ABCC11, an axillary osmidrosis risk factor.
Human cell - 1 Jul 2024
Toyoda Yu, Matsuo Hirotaka, Takada Tappei
Abstract excerpt
Human ATP-binding cassette transporter C11 (ABCC11) is a membrane protein exhibiting ATP-dependent transport activity for a variety of lipophilic anions including endogenous substances and xenobiotics such as anti-cancer agents. Accumulating evidence indicates that ABCC11 wild type is responsible for the high-secretion phenotypes in human apocrine glands including wet type of earwax and the risk of axillary...
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