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Clinical implications of CSF-ctDNA positivity in newly diagnosed diffuse large B cell lymphoma.

Leukemia - 1 Jul 2024

Liang Jin-Hua, Wu Yi-Fan, Shen Hao-Rui, Li Yue, Liang Jun-Heng, Gao Rui, Hua Wei, Shang Chun-Yu, Du Kai-Xin, Xing Tong-Yao, Zhang Xin-Yu, Wang Chen-Xuan, Zhu Liu-Qing, Shao Yang W, Li Jian-Yong, Wu Jia-Zhu, Yin Hua, Wang Li, Xu Wei

Abstract excerpt

The clinical implications of CSF-ctDNA positivity in newly diagnosed diffuse large B cell lymphoma (ND-DLBCL) remains largely unexplored. One hundred ND-DLBCL patients were consecutively enrolled as training cohort and another 26 ND-DLBCL patients were prospectively enrolled in validation cohort. CSF-ctDNA positivity (CSF(+)) was identified in 25 patients (25.0%) in the training cohort and 7 patients (26.9%) in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38750139
DOI: 10.1038/s41375-024-02279-7

Genes

CARD11
FAT4
ID3
JAK2
PLCG2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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