Article
Polygenic risk score for predicting weight loss after bariatric surgery.
JCI insight - 6 Sept 2018
de Toro-Martín Juan, Guénard Frédéric, Tchernof André, Pérusse Louis, Marceau Simon, Vohl Marie-Claude
Abstract excerpt
BACKGROUND: The extent of weight loss among patients undergoing bariatric surgery is highly variable. Herein, we tested the contribution of genetic background to such interindividual variability after biliopancreatic diversion with duodenal switch. METHODS: Percentage of excess body weight loss (%EBWL) was monitored in 865 patients over a period of 48 months after bariatric surgery, and two polygenic risk scores...
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