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Article

Hypogonadotropic hypogonadism in male tilapia lacking a functional rln3b gene.

International journal of biological macromolecules - 1 Jun 2024

Xu Qinglei, Ye Maolin, Su Yun, Feng Li, Zhou Linyan, Xu Jian, Wang Deshou

Abstract excerpt

Relaxin 3 is a neuropeptide that plays a crucial role in reproductive functions of mammals. Previous studies have confirmed that rln3a plays an important role in the male reproduction of tilapia. To further understand the significance of its paralogous gene rln3b in male fertility, we generated a homozygous mutant line of rln3b in Nile tilapia. Our findings indicated that rln3b mutation delayed spermatogenesis...

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Identifiers

PMID: 38729472
DOI: 10.1016/j.ijbiomac.2024.132165

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