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Article

A mendelian randomization study revealing that metabolic syndrome is causally related to renal failure.

Frontiers in endocrinology - 1 Jan 2024

Cai Xianfu, Wang Decai, Wang Jianjun, Ding Chenguang, Li Yang, Zheng Jin, Xue Wujun

Abstract excerpt

Background: The onset and progression of chronic kidney disease (CKD) has been linked to metabolic syndrome (MetS), with the results of recent observational studies supporting a potential link between renal failure and MetS. The causal nature of this relationship, however, remains uncertain. This study thus leveraged a Mendelian Randomization (MR) approach to probe the causal link of MetS with renal failure....

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Share to Chronic Kidney Disease and Diabetes
Share to Genetic Associations and Epidemiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Metabolic Syndrome

Share to Polymorphism, Single Nucleotide

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Source

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Identifiers

PMID: 38911042
DOI: 10.3389/fendo.2024.1392466
PMCID: PMC11190295

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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