Article
Causal Effects of Basal Metabolic Rate on Cardiovascular Disease: A Bidirectional Mendelian Randomization Study.
Journal of the American Heart Association - 2 Jan 2024
Zhao Peng, Han Feiyuan, Liang Xinyu, Meng Li, Yu Bo, Liu Xinxin, Tian Jinwei
Abstract excerpt
BACKGROUND: Despite the health effects of basal metabolic rate (BMR), the causal effect of BMR on cardiovascular diseases (CVDs) remains undetermined. To elucidate the causal nature, Mendelian randomization (MR) analyses were performed. METHODS AND RESULTS: Summary genome-wide association statistics regarding BMR and 5 CVDs were obtained from European databases. A 2-sample bidirectional MR was performed to assess...
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