Article
Alcohol milestones and internalizing, externalizing, and executive function: longitudinal and polygenic score associations.
Psychological medicine - 1 Jul 2024
Paul Sarah E, Baranger David A A, Johnson Emma C, Jackson Joshua J, Gorelik Aaron J, Miller Alex P, Hatoum Alexander S, Thompson Wesley K, Strube Michael, Dick Danielle M, Kamarajan Chella, Kramer John R, Plawecki Martin H, Chan Grace, Anokhin Andrey P, Chorlian David B, Kinreich Sivan, Meyers Jacquelyn L, Porjesz Bernice, Edenberg Howard J, Agrawal Arpana, Bucholz Kathleen K, Bogdan Ryan
Abstract excerpt
BACKGROUND: Although the link between alcohol involvement and behavioral phenotypes (e.g. impulsivity, negative affect, executive function [EF]) is well-established, the directionality of these associations, specificity to stages of alcohol involvement, and extent of shared genetic liability remain unclear. We estimate longitudinal associations between transitions among alcohol milestones, behavioral phenotypes,...
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