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Article

Genomic landscape and functional characterization of structural variations in schizophrenia and bipolar disorder.

Psychiatry research - 1 Jul 2024

Wu Yong, Zhang Chu-Yi, Zhang Yue, Chen Rui, Wang Lu, Chang Hong, Li Ming, Xiao Xiao, Li Shi-Wu

Abstract excerpt

Multiple types of variations have been postulated to confer risk of schizophrenia and bipolar disorder, but majority of present GWAS solely focused on SNPs or small indels, and the impacts of structural variations (SVs) remain less understood. Nevertheless, accumulating evidence suggest that SVs may explain the association signals in certain GWAS hits. Here, we conducted pairwise linkage disequilibrium (LD)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38718554
DOI: 10.1016/j.psychres.2024.115929

Genes

BORCS7
GNL3

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