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Article

The nasal basal cell population shifts toward a diseased phenotype with impaired barrier formation capacity in allergic rhinitis.

The Journal of allergy and clinical immunology - 1 Sept 2024

Ruysseveldt Emma, Steelant Brecht, Wils Tine, Cremer Jonathan, Bullens Dominique M A, Hellings Peter W, Martens Katleen

Abstract excerpt

BACKGROUND: The integrity of the airway epithelium is guarded by the airway basal cells that serve as progenitor cells and restore wounds in case of injury. Basal cells are a heterogenous population, and specific changes in their behavior are associated with chronic barrier disruption-mechanisms that have not been studied in detail in allergic rhinitis (AR). OBJECTIVE: We aimed to study basal cell subtypes in AR...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38705259
DOI: 10.1016/j.jaci.2024.04.021

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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